June 2019

New Indications

  • Fingolimod (Gilenya) is now indicated for the treatment of children ≥ 10 years of age with relapsing forms of multiple sclerosis, to reduce the frequency of relapses and to delay the progression of disability.
     
  • Fondaparinux sodium (Arixtra) is now indicated for the treatment of unstable angina or non-ST segment elevation myocardial infarction in patients for whom urgent (< 120 minutes) invasive management (percutaneous coronary intervention) is not indicated, and for the treatment of ST segment elevation myocardial infarction in patients managed without any form of initial reperfusion therapy.
     
  • Nitric oxide (INOmax), in conjunction with ventilatory support and other appropriate agents, is now indicated to selectively decrease pulmonary arterial pressure in adult patients with perioperative pulmonary hypertension in conjunction with heart surgery.

New Contraindications

  • Articaine HCl and adrenaline (epinephrine) (Septanest) is now contraindicated in phaeochromocytoma, and complete heart block (not compensated by a pacemaker).
     
  • Tolvaptan (Jinarc) is now contraindicated in patients with hypersensitivity to benzazepine derivatives.

Don't Rush to Crush Updates

These are the new and updated monographs.
  DRTC Monograph Name   New/Revised
  Letermovir   New
  Milnacipran   New
  Neratinib   New
  Pazopanib   Revised
  Risperidone   Revised

This list is a summary of only some of the changes that have occurred over the last month. Before prescribing, always refer to the full product information.

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