August 2018

New Contraindications

Clarithromycin (Klacid) is now contraindicated with concurrent administration of domperidone.

Diclofenac sodium (Voltaren) and diclofenac potassium (Voltaren Rapid) are now contraindicated in patients in whom diclofenac, aspirin or other NSAIDs induce angioedema.

Eicosapentaenoic acid (EPA) ethyl ester/docosahexaenoic acid (DHA) ethyl ester (Omacor) is now contraindicated with hypersensitivity to peanut.

Eliglustat (Cerdelga) is now contraindicated in the following: CYP2D6 intermediate metabolisers or poor metabolisers with any degree of hepatic impairment, since metabolism is the predominant route of elimination; CYP2D6 extensive metabolisers (EMs) with moderate or severe hepatic impairment and in CYP2D6 EMs with mild hepatic impairment taking a strong or moderate CYP2D6 inhibitor.

This list is a summary of only some of the changes that have occurred over the last month. Before prescribing, always refer to the full product information.

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