New Product - Prometrium
Prometrium (progesterone (micronised)). Progesterone is a naturally occurring steroid hormone that is secreted by the ovary, placenta and adrenal gland. It acts on the endometrium by converting the proliferating phase to the secretory phase. Progesterone is necessary to increase endometrial receptivity for implantation of an embryo, and once an embryo is implanted, progesterone acts to maintain the pregnancy. As well as gestagenic actions, progesterone also has antiestrogenic, slightly antiandrogenic and antialdosterone effects. Prometrium is indicated for the treatment of menstrual irregularities in women with menstrual abnormalities or secondary amenorrhoea due to normogonadotrophic amenorrhoea. It is also indicated for hormone replacement therapy‑adjunctive use with an oestrogen in postmenopausal women with an intact uterus. Prometrium is contraindicated in any of the following conditions: severe hepatic dysfunction; undiagnosed vaginal bleeding; known missed abortion or ectopic pregnancy; mammary or genital tract carcinoma; thromboembolic disorders; thrombophlebitis; cerebral haemorrhage; and porphyria. Prometrium is available as 100 mg soft capsules in packs of 30’s.
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