May 2016May 2016
New Product - EllaOne
EllaOne (ulipristal acetate) is an orally active synthetic selective progesterone receptor modulator that acts via high affinity (nanomolar) binding to the human progesterone receptor. Its major metabolite, monodesmethyl ulipristal, has comparable affinity for the progesterone receptor. When used for emergency contraception the mechanism of action is inhibition or delay of ovulation via suppression of the lutenising hormone (LH) surge. Ulipristal acetate has weak affinity for the androgen receptor and negligible affinity for the human oestrogen and mineralocorticoid receptors. EllaOne is indicated for emergency contraception within 120 hours (5 days) of unprotected sexual intercourse or contraceptive failure. EllaOne should not be given to pregnant women. If menstrual bleeding is overdue, if the last menstrual period was abnormal in timing or character or if pregnancy is suspected for any other reason, pregnancy should be excluded (by pregnancy testing or pelvic examination) before treatment is given. EllaOne 30 mg tablet is available as a blister pack of 1.
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