February 2015February 2015
New Product - Iclusig
Iclusig (ponatinib (as hydrochloride)) is a BCR‑ABL tyrosine kinase inhibitor. Iclusig is indicated for the treatment of adults with chronic phase, accelerated phase, or blast phase chronic myeloid Ieukaemia whose disease is resistant to, or who are intolerant of at least two prior tyrosine kinase inhibitors; or where there is a T315I mutation; and in adults with Philadelphia chromosome positive (Ph+) ALL whose disease is resistant to, or who are intolerant of dasatinib and for whom subsequent treatment with imatinib is not clinically appropriate; or where there is a T315I mutation. Therapy with Iclusig should be initiated and monitored by a haematologist with expertise in managing adult Ieukaemias. Iclusig is available as 15 mg tablets in bottles of 60’s and 45 mg tablets in bottles of 30’s.
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