November 2014

Safety Related Changes

Do not coadminister Avapro HCT (irbesartan/ hydrochlorothiazide) with ACE inhibitors in patients with diabetic nephropathy.

Mersyndol Forte (paracetamol, codeine phosphate, doxylamine succinate) is now contraindicated in children under 18 years undergoing tonsillectomy and/or adenoidectomy to treat obstructive sleep apnoea, and in patients who are ultrarapid CYP2D6 metabolisers.

This list is a summary of only some of the changes that have occurred over the last month. Before prescribing, always refer to the full product information.

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